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Unable to open Exchange Management Console

Method 1:

Close all MMC/EMC instances before proceeding.
Open Registry Editor (regedit) as the user you run the EMC under.
Go to HKEY_CURRENT_USER\SOFTWARE\Microsoft\ExchangeServer\v14\AdminTools
Look for value NodeStructureSetting.
If it is there, back it up and then remove it.

Method 2:
Close all MMC/EMC Instances before proceeding.
Open Powershell or Powershell IDE as the user you run the EMC under and execute the following command:
Remove-ItemProperty -Path HKCU:\Software\Microsoft\ExchangeServer\v14\AdminTools\ -Name NodeStructureSettings
Close Powershell